Topical imiquimod for the palliative treatment of recurrent oral squamous cell carcinoma
نویسندگان
چکیده
CT: computerized tomography OSCC: oral squamous cell carcinoma RMT: retromolar trigone INTRODUCTION Oral squamous cell carcinoma (OSCC) has historically been treated with surgery or radiation with or without chemotherapy, all of which lead to significant posttreatment morbidity. Topical imiquimod cream has been approved by the Food and Drug Administration for treatment of nonhyperkeratotic actinic keratosis, superficial basal cell carcinoma, and external genital warts. Off-label use has demonstrated effectiveness in treatment of mucosal neoplasms. Given the considerable risks associated with standard treatment regimens for OSCC, topical imiquimodmight offer a reasonable andwell-tolerated palliative treatment option for patients with multiple comorbidities. We report the resolution of recurrent OSCC with topical imiquimod cream.
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